Immunoglobulins localizing in periapical lesions

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Detection of immunoglobulins from explant cultures of periapical lesions.

The presence of immunoreactive cells in periapical inflammatory lesions suggests that immune responses participate in the disease process. The purpose of this study was to determine the presence and concentration of immunoglobulins in the supernatant fluids of explant cultures of periapical lesions. Ninety periapical lesions that had been contiguous with the apex of a root were removed and main...

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Thirty tissue samples were examined histologically and classified as being inflamed (apical granulomas) or noninflamed (scars or noninflamed cysts). The samples were then homogenized in pyrogen-free water and treated to remove interfering substances. The presence of endotoxin was then determined by means of the limulus assay; 75 percent of the inflamed tissues were positive for endotoxin, while...

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ژورنال

عنوان ژورنال: Japanese Journal of Oral & Maxillofacial Surgery

سال: 1981

ISSN: 2186-1579,0021-5163

DOI: 10.5794/jjoms.27.1370